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A paradigm of thermal adaptation in penguins and elephants by tuning cold activation in TRPM8
To adapt to habitat temperature, vertebrates have developed sophisticated physiological and ecological mechanisms through evolution. Transient receptor potential melastatin 8 (TRPM8) serves as the primary sensor for cold. However, how cold activates TRPM8 and how this sensor is tuned for thermal ada...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165450/ https://www.ncbi.nlm.nih.gov/pubmed/32220960 http://dx.doi.org/10.1073/pnas.1922714117 |