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A paradigm of thermal adaptation in penguins and elephants by tuning cold activation in TRPM8

To adapt to habitat temperature, vertebrates have developed sophisticated physiological and ecological mechanisms through evolution. Transient receptor potential melastatin 8 (TRPM8) serves as the primary sensor for cold. However, how cold activates TRPM8 and how this sensor is tuned for thermal ada...

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Detalles Bibliográficos
Autores principales: Yang, Shilong, Lu, Xiancui, Wang, Yunfei, Xu, Lizhen, Chen, Xiaoying, Yang, Fan, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165450/
https://www.ncbi.nlm.nih.gov/pubmed/32220960
http://dx.doi.org/10.1073/pnas.1922714117