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Serum phosphorylated neurofilament heavy-chain levels reflect phenotypic heterogeneity and are an independent predictor of survival in motor neuron disease

To investigate the prognostic role and the major determinants of serum phosphorylated neurofilament heavy -chain (pNfH) concentration across a large cohort of motor neuron disease (MND) phenotypes. Enzyme-linked immunosorbent assay (ELISA) was used to measure serum pNfH concentration in 219 MND pati...

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Detalles Bibliográficos
Autores principales: Falzone, Yuri Matteo, Domi, Teuta, Agosta, Federica, Pozzi, Laura, Schito, Paride, Fazio, Raffaella, Del Carro, Ubaldo, Barbieri, Alessandra, Comola, Mauro, Leocani, Letizia, Comi, Giancarlo, Carrera, Paola, Filippi, Massimo, Quattrini, Angelo, Riva, Nilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166001/
https://www.ncbi.nlm.nih.gov/pubmed/32306171
http://dx.doi.org/10.1007/s00415-020-09838-9