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Gene expressing human artificial chromosome vectors: Advantages and challenges for gene therapy
After the construction of genomic libraries with yeast artificial chromosomes in the late 1980's for gene isolation and expression studies in cells, human artificial chromosomes were then a natural development in the 1990's, based on the same principles of formation requiring centromeric s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academic Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166075/ https://www.ncbi.nlm.nih.gov/pubmed/32126238 http://dx.doi.org/10.1016/j.yexcr.2020.111931 |