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Gene Regulatory and Expression Differences between Mouse and Pig Limb Buds Provide Insights into the Evolutionary Emergence of Artiodactyl Traits

Digit loss/reductions are evolutionary adaptations in cursorial mammals such as pigs. To gain mechanistic insight into these processes, we performed a comparative molecular analysis of limb development in mouse and pig embryos, which revealed a loss of anterior-posterior polarity during distal progr...

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Detalles Bibliográficos
Autores principales: Tissières, Virginie, Geier, Florian, Kessler, Barbara, Wolf, Eckhard, Zeller, Rolf, Lopez-Rios, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166081/
https://www.ncbi.nlm.nih.gov/pubmed/32268095
http://dx.doi.org/10.1016/j.celrep.2020.03.054