Cargando…

Structural Insights into the Mammalian Late-Stage Initiation Complexes

In higher eukaryotes, the mRNA sequence in the direct vicinity of the start codon, called the Kozak sequence (CRCCaugG, where R is a purine), is known to influence the rate of the initiation process. However, the molecular basis underlying its role remains poorly understood. Here, we present the cry...

Descripción completa

Detalles Bibliográficos
Autores principales: Simonetti, Angelita, Guca, Ewelina, Bochler, Anthony, Kuhn, Lauriane, Hashem, Yaser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166083/
https://www.ncbi.nlm.nih.gov/pubmed/32268096
http://dx.doi.org/10.1016/j.celrep.2020.03.061