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Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine

BACKGROUND: Combinations of hydroxychloroquine (HCQ) and azithromycin have been promoted as treatments for COVID-19 based on small, uncontrolled clinical trials that have not assessed potential risks. Risks of treatment include QT segment prolongation, Torsades de Pointes (TdP), and death. This comp...

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Detalles Bibliográficos
Autores principales: Sarayani, Amir, Cicali, Brian, Henriksen, Carl H., Brown, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166303/
https://www.ncbi.nlm.nih.gov/pubmed/32327397
http://dx.doi.org/10.1016/j.sapharm.2020.04.016