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The role of mouse models in colorectal cancer research—The need and the importance of the orthotopic models

Colorectal cancer is a worldwide health burden, with high incidence and mortality, especially in the advanced stages of the disease. Preclinical models are very important and valuable to discover and validate early and specific biomarkers as well as new therapeutic targets. In order to accomplish th...

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Detalles Bibliográficos
Autores principales: Oliveira, Rui C., Abrantes, Ana Margarida, Tralhão, José Guilherme, Botelho, Maria Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167241/
https://www.ncbi.nlm.nih.gov/pubmed/32318654
http://dx.doi.org/10.1002/ame2.12102