Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

Human schistosomiasis is a disease which globally affects over 229 million people. Three major species affecting humans are Schistosoma mansoni, S. haematobium and S. japonicum. Previous treatment of S. mansoni includes the use of oxamniquine (OXA), a prodrug that is enzymatically activated in S. ma...

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Detalles Bibliográficos
Autores principales: Rugel, Anastasia R., Guzman, Meghan A., Taylor, Alexander B., Chevalier, Frédéric D., Tarpley, Reid S., McHardy, Stanton F., Cao, Xiaohang, Holloway, Stephen P., Anderson, Timothy J.C., Hart, P. John, LoVerde, Philip T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167500/
https://www.ncbi.nlm.nih.gov/pubmed/32315953
http://dx.doi.org/10.1016/j.ijpddr.2020.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167500/
https://www.ncbi.nlm.nih.gov/pubmed/32315953
http://dx.doi.org/10.1016/j.ijpddr.2020.04.001

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