Rifabutin Suppresses Inducible Clarithromycin Resistance in Mycobacterium abscessus by Blocking Induction of whiB7 and erm41

Clarithromycin (CLR) is the corner stone in regimens for the treatment of lung disease caused by Mycobacterium abscessus (Mab). However, many strains harbor the CLR-inducible CLR resistance gene erm41, encoding a ribosome methylase. Induction of erm41 is mediated by the transcription factor whiB7. W...

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Detalles Bibliográficos
Autores principales: Aziz, Dinah Binte, Go, Mei Lin, Dick, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168051/
https://www.ncbi.nlm.nih.gov/pubmed/32050554
http://dx.doi.org/10.3390/antibiotics9020072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168051/
https://www.ncbi.nlm.nih.gov/pubmed/32050554
http://dx.doi.org/10.3390/antibiotics9020072

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