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The VNTR 48 bp Polymorphism in the DRD4 Gene Is Associated with Higher Tobacco Smoking in Male Mexican Mestizo Smokers with and without COPD

Cigarette smoking is influenced by nicotine’s effects on dopaminergic activity, which appear to be moderated by genetic variation, particularly a variable number tandem repeat (VNTR, 48 bp) polymorphism in the third exon of the dopamine receptor gene (DRD4). Smokers with the VNTR ≥7 repeats (long, L...

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Detalles Bibliográficos
Autores principales: Pérez-Rubio, Gloria, García-Carmona, Salvador, García-Gómez, Leonor, Hernández-Pérez, Andrea, Ramírez-Venegas, Alejandra, López-Flores, Luis Alberto, Sansores, Raúl, Falfán-Valencia, Ramcés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168062/
https://www.ncbi.nlm.nih.gov/pubmed/31905892
http://dx.doi.org/10.3390/diagnostics10010016