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Aptamer-Conjugated Tb(III)-Doped Silica Nanoparticles for Luminescent Detection of Leukemia Cells

DNA aptamers have many benefits for cell imaging, such as high affinity and specificity, easiness of chemical functionalization, and low cost of production. Among known aptamers, Sgc8-aptamer was selected against acute lymphoblastic leukemia cells with a dissociation constant in a nanomolar range. T...

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Detalles Bibliográficos
Autores principales: Grechkin, Yaroslav A., Grechkina, Svetlana L., Zaripov, Emil A., Fedorenko, Svetlana V., Mustafina, Asiya R., Berezovski, Maxim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168109/
https://www.ncbi.nlm.nih.gov/pubmed/31941078
http://dx.doi.org/10.3390/biomedicines8010014