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Comprehensive Analysis of Neurotoxin-Induced Ablation of Dopaminergic Neurons in Zebrafish Larvae

Neurotoxin exposure of zebrafish larvae has been used to mimic a Parkinson’s disease (PD) phenotype and to facilitate high-throughput drug screening. However, the vulnerability of zebrafish to various neurotoxins was shown to be variable. Here, we provide a direct comparison of ablative effectivenes...

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Detalles Bibliográficos
Autores principales: Kalyn, Michael, Hua, Khang, Mohd Noor, Suzita, Wong, Chee Ern David, Ekker, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168159/
https://www.ncbi.nlm.nih.gov/pubmed/31905670
http://dx.doi.org/10.3390/biomedicines8010001