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Effect of α-Bisabolol and Its β-Cyclodextrin Complex as TetK and NorA Efflux Pump Inhibitors in Staphylococcus aureus Strains

Efflux pumps are proteins present in the plasma membrane of bacteria, which transport antibiotics and other compounds into the extracellular medium, conferring resistance. The discovery of natural efflux pump inhibitors is a promising alternative. α-Bisabolol is a sesquiterpene isolated from several...

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Detalles Bibliográficos
Autores principales: Pereira da Cruz, Rafael, Sampaio de Freitas, Thiago, do Socorro Costa, Maria, Lucas dos Santos, Antonia Thassya, Ferreira Campina, Fábia, Pereira, Raimundo Luiz Silva, Bezerra, José Weverton Almeida, Quintans-Júnior, Lucindo José, De Souza Araújo, Adriano Antunes, De Siqueira Júnior, José Pinto, Iriti, Marcello, Varoni, Elena Maria, De Menezes, Irwin Rose Alencar, Melo Coutinho, Henrique Douglas, Bezerra Morais-Braga, Maria Flaviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168184/
https://www.ncbi.nlm.nih.gov/pubmed/31947642
http://dx.doi.org/10.3390/antibiotics9010028