Identification and Heterologous Expression of the Biosynthetic Gene Cluster Encoding the Lasso Peptide Humidimycin, a Caspofungin Activity Potentiator

Humidimycin (MDN-0010) is a ribosomally synthesized and post-translationally modified peptide (RiPP) belonging to class I lasso peptides, and is structurally related to siamycins, which have been shown to have strong antimicrobial activities against Gram-positive bacteria and to possess anti-HIV act...

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Detalles Bibliográficos
Autores principales: Sánchez-Hidalgo, Marina, Martín, Jesús, Genilloud, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168211/
https://www.ncbi.nlm.nih.gov/pubmed/32046042
http://dx.doi.org/10.3390/antibiotics9020067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168211/
https://www.ncbi.nlm.nih.gov/pubmed/32046042
http://dx.doi.org/10.3390/antibiotics9020067

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