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Conjugation of Penicillin-G with Silver(I) Ions Expands Its Antimicrobial Activity against Gram Negative Bacteria

Conjugation of penicillin G (PenH) with silver(I) ions forms a new CoMeD (conjugate of metal with a drug) with formula [Ag(pen)(CH(3)OH)](2) (PenAg). PenAg was characterized by a plethora of physical and spectroscopic techniques, which include in the solid state m.p.; elemental analysis; X-ray fluor...

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Detalles Bibliográficos
Autores principales: Ketikidis, Ioannis, Banti, Christina N., Kourkoumelis, Nikolaos, Tsiafoulis, Constantinos G., Papachristodoulou, Christina, Kalampounias, Angelos G., Hadjikakou, Sotiris K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168214/
https://www.ncbi.nlm.nih.gov/pubmed/31941048
http://dx.doi.org/10.3390/antibiotics9010025