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Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV LL3B3D A(24)) Is Highly Attenuated in Pigs

Inactivated whole-virus vaccines are widely used for the control of foot-and-mouth disease (FMD). Their production requires the growth of large quantities of virulent FMD virus in biocontainment facilities, which is expensive and carries the risk of an inadvertent release of virus. Attenuated recomb...

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Detalles Bibliográficos
Autores principales: Eschbaumer, Michael, Dill, Veronika, Carlson, Jolene C., Arzt, Jonathan, Stenfeldt, Carolina, Krug, Peter W., Hardham, John M., Stegner, Jacob E., Rodriguez, Luis L., Rieder, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168223/
https://www.ncbi.nlm.nih.gov/pubmed/32079312
http://dx.doi.org/10.3390/pathogens9020129