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Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV LL3B3D A(24)) Is Highly Attenuated in Pigs
Inactivated whole-virus vaccines are widely used for the control of foot-and-mouth disease (FMD). Their production requires the growth of large quantities of virulent FMD virus in biocontainment facilities, which is expensive and carries the risk of an inadvertent release of virus. Attenuated recomb...
Autores principales: | Eschbaumer, Michael, Dill, Veronika, Carlson, Jolene C., Arzt, Jonathan, Stenfeldt, Carolina, Krug, Peter W., Hardham, John M., Stegner, Jacob E., Rodriguez, Luis L., Rieder, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168223/ https://www.ncbi.nlm.nih.gov/pubmed/32079312 http://dx.doi.org/10.3390/pathogens9020129 |
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