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A Versatile Model of Microfluidic Perifusion System for the Evaluation of C-Peptide Secretion Profiles: Comparison Between Human Pancreatic Islets and HLSC-Derived Islet-Like Structures

A robust and easy-to-use tool for the ex vivo dynamic evaluation of pancreatic islet (PI) function is essential for further development of novel cell-based therapeutic approaches to treating diabetes. Here, we developed four different glucose perifusion protocols (GPPs) in a microfluidic perifusion...

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Detalles Bibliográficos
Autores principales: Gomez, Yonathan, Navarro-Tableros, Victor, Tetta, Ciro, Camussi, Giovanni, Brizzi, Maria Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168272/
https://www.ncbi.nlm.nih.gov/pubmed/32046184
http://dx.doi.org/10.3390/biomedicines8020026