The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer

Autophagy, a process of cellular self-degradation and cell survival whereby the cell generates energy and metabolic intermediates under conditions of stress (i.e., nutrient deprivation), is also commonly induced in tumor cells in response to chemotherapy and radiation. While chemotherapy-induced aut...

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Detalles Bibliográficos
Autor principal: Gewirtz, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168293/
https://www.ncbi.nlm.nih.gov/pubmed/31947952
http://dx.doi.org/10.3390/biology9010012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168293/
https://www.ncbi.nlm.nih.gov/pubmed/31947952
http://dx.doi.org/10.3390/biology9010012

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