Production of Squalene in Bacillus subtilis by Squalene Synthase Screening and Metabolic Engineering

[Image: see text] Squalene synthase (SQS) catalyzes the conversion of two farnesyl pyrophosphates to squalene, an important intermediate in between isoprene and valuable triterpenoids. In this study, we have constructed a novel biosynthesis pathway for squalene in Bacillus subtilis and performed met...

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Detalles Bibliográficos
Autores principales: Song, Yafeng, Guan, Zheng, van Merkerk, Ronald, Pramastya, Hegar, Abdallah, Ingy I., Setroikromo, Rita, Quax, Wim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168599/
https://www.ncbi.nlm.nih.gov/pubmed/32208656
http://dx.doi.org/10.1021/acs.jafc.0c00375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168599/
https://www.ncbi.nlm.nih.gov/pubmed/32208656
http://dx.doi.org/10.1021/acs.jafc.0c00375

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