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Production of Squalene in Bacillus subtilis by Squalene Synthase Screening and Metabolic Engineering
[Image: see text] Squalene synthase (SQS) catalyzes the conversion of two farnesyl pyrophosphates to squalene, an important intermediate in between isoprene and valuable triterpenoids. In this study, we have constructed a novel biosynthesis pathway for squalene in Bacillus subtilis and performed met...
Autores principales: | Song, Yafeng, Guan, Zheng, van Merkerk, Ronald, Pramastya, Hegar, Abdallah, Ingy I., Setroikromo, Rita, Quax, Wim J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168599/ https://www.ncbi.nlm.nih.gov/pubmed/32208656 http://dx.doi.org/10.1021/acs.jafc.0c00375 |
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