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Minimum Determinants of Transmissible Gastroenteritis Virus Enteric Tropism Are Located in the N-Terminus of Spike Protein

Transmissible gastroenteritis virus (TGEV) is an enteric coronavirus causing high morbidity and mortality in porcine herds worldwide, that possesses both enteric and respiratory tropism. The ability to replicate in the enteric tract directly correlates with virulence, as TGEVs with an exclusive resp...

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Detalles Bibliográficos
Autores principales: Sanchez, Carlos M., Pascual-Iglesias, Alejandro, Sola, Isabel, Zuñiga, Sonia, Enjuanes, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168613/
https://www.ncbi.nlm.nih.gov/pubmed/31861369
http://dx.doi.org/10.3390/pathogens9010002