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Lower [(18)F]fallypride binding to dopamine D(2/3) receptors in frontal brain areas in adults with 22q11.2 deletion syndrome: a positron emission tomography study

BACKGROUND: The 22q11.2 deletion syndrome (22q11DS) is caused by a deletion on chromosome 22 locus q11.2. This copy number variant results in haplo-insufficiency of the catechol-O-methyltransferase (COMT) gene, and is associated with a significant increase in the risk for developing cognitive impair...

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Detalles Bibliográficos
Autores principales: van Duin, Esther D. A., Ceccarini, Jenny, Booij, Jan, Kasanova, Zuzana, Vingerhoets, Claudia, van Huijstee, Jytte, Heinzel, Alexander, Mohammadkhani-Shali, Siamak, Winz, Oliver, Mottaghy, Felix, Myin-Germeys, Inez, van Amelsvoort, Thérèse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168654/
https://www.ncbi.nlm.nih.gov/pubmed/30935427
http://dx.doi.org/10.1017/S003329171900062X