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Lower [(18)F]fallypride binding to dopamine D(2/3) receptors in frontal brain areas in adults with 22q11.2 deletion syndrome: a positron emission tomography study
BACKGROUND: The 22q11.2 deletion syndrome (22q11DS) is caused by a deletion on chromosome 22 locus q11.2. This copy number variant results in haplo-insufficiency of the catechol-O-methyltransferase (COMT) gene, and is associated with a significant increase in the risk for developing cognitive impair...
Autores principales: | van Duin, Esther D. A., Ceccarini, Jenny, Booij, Jan, Kasanova, Zuzana, Vingerhoets, Claudia, van Huijstee, Jytte, Heinzel, Alexander, Mohammadkhani-Shali, Siamak, Winz, Oliver, Mottaghy, Felix, Myin-Germeys, Inez, van Amelsvoort, Thérèse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168654/ https://www.ncbi.nlm.nih.gov/pubmed/30935427 http://dx.doi.org/10.1017/S003329171900062X |
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