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Diazoxide affects mitochondrial bioenergetics by the opening of mKATP channel on submicromolar scale

BACKGROUND: Cytoprotection afforded by mitochondrial ATP-sensitive K(+)-channel (mK(ATP)-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and ROS production. However, generally these effects were studied in the pr...

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Detalles Bibliográficos
Autores principales: Akopova, Olga, Kolchinskaya, Liudmila, Nosar, Valentina, Mankovska, Iryna, Sagach, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168813/
https://www.ncbi.nlm.nih.gov/pubmed/32306897
http://dx.doi.org/10.1186/s12860-020-00275-0