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Diazoxide affects mitochondrial bioenergetics by the opening of mKATP channel on submicromolar scale
BACKGROUND: Cytoprotection afforded by mitochondrial ATP-sensitive K(+)-channel (mK(ATP)-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and ROS production. However, generally these effects were studied in the pr...
Autores principales: | Akopova, Olga, Kolchinskaya, Liudmila, Nosar, Valentina, Mankovska, Iryna, Sagach, Vadim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168813/ https://www.ncbi.nlm.nih.gov/pubmed/32306897 http://dx.doi.org/10.1186/s12860-020-00275-0 |
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