Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability

BACKGROUND: In sepsis, the endothelial barrier becomes incompetent, with the leaking of plasma into interstitial tissues. VE-cadherin, an adherens junction protein, is the gatekeeper of endothelial cohesion. Kinins, released during sepsis, induce vascular leakage and vasodilation. They act via two G...

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Detalles Bibliográficos
Autores principales: Ruiz, Stéphanie, Vardon-Bounes, Fanny, Buléon, Marie, Guilbeau-Frugier, Céline, Séguelas, Marie-Hélène, Conil, Jean-Marie, Girolami, Jean-Pierre, Tack, Ivan, Minville, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168845/
https://www.ncbi.nlm.nih.gov/pubmed/32306971
http://dx.doi.org/10.1186/s12967-020-02342-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168845/
https://www.ncbi.nlm.nih.gov/pubmed/32306971
http://dx.doi.org/10.1186/s12967-020-02342-8

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