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GRP78 expression in peripheral blood mononuclear cells is a new predictive marker for the benefit of taxanes in breast cancer neoadjuvant treatment

BACKGROUND: Breast cancer treatment is tailored to the specific cancer subtype. Often, systemic treatment is given prior to surgery. Chemotherapy induces significant endoplasmic reticulum (ER) stress-mediated cell death and upregulation of 78-kDa glucose-regulated protein (GRP78). We hypothesized th...

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Detalles Bibliográficos
Autores principales: Raiter, Annat, Lipovetzki, Julia, Lubin, Ido, Yerushalmi, Rinat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168854/
https://www.ncbi.nlm.nih.gov/pubmed/32306920
http://dx.doi.org/10.1186/s12885-020-06835-z