Short paired-end reads trump long single-end reads for expression analysis

BACKGROUND: Typical experimental design advice for expression analyses using RNA-seq generally assumes that single-end reads provide robust gene-level expression estimates in a cost-effective manner, and that the additional benefits obtained from paired-end sequencing are not worth the additional co...

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Detalles Bibliográficos
Autores principales: Freedman, Adam H., Gaspar, John M., Sackton, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168855/
https://www.ncbi.nlm.nih.gov/pubmed/32306895
http://dx.doi.org/10.1186/s12859-020-3484-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168855/
https://www.ncbi.nlm.nih.gov/pubmed/32306895
http://dx.doi.org/10.1186/s12859-020-3484-z

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