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Short paired-end reads trump long single-end reads for expression analysis
BACKGROUND: Typical experimental design advice for expression analyses using RNA-seq generally assumes that single-end reads provide robust gene-level expression estimates in a cost-effective manner, and that the additional benefits obtained from paired-end sequencing are not worth the additional co...
Autores principales: | Freedman, Adam H., Gaspar, John M., Sackton, Timothy B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168855/ https://www.ncbi.nlm.nih.gov/pubmed/32306895 http://dx.doi.org/10.1186/s12859-020-3484-z |
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