Cargando…

Promoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line

BACKGROUND: Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major cause of Merkel cell carcinoma (MCC), an aggressive skin cancer. Se...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdulsalam, Ibrahim, Rasheed, Kashif, Sveinbjørnsson, Baldur, Ehlers, Bernhard, Moens, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168875/
https://www.ncbi.nlm.nih.gov/pubmed/32306957
http://dx.doi.org/10.1186/s12985-020-01317-x