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On the utility of RNA sample pooling to optimize cost and statistical power in RNA sequencing experiments

BACKGROUND: In gene expression studies, RNA sample pooling is sometimes considered because of budget constraints or lack of sufficient input material. Using microarray technology, RNA sample pooling strategies have been reported to optimize both the cost of data generation as well as the statistical...

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Detalles Bibliográficos
Autores principales: Assefa, Alemu Takele, Vandesompele, Jo, Thas, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168886/
https://www.ncbi.nlm.nih.gov/pubmed/32306892
http://dx.doi.org/10.1186/s12864-020-6721-y