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Production and Characterization of Chitosan–Polyanion Nanoparticles by Polyelectrolyte Complexation Assisted by High-Intensity Sonication for the Modified Release of Methotrexate

A promising strategy to improve the effectivity of anticancer treatment and decrease its side effects is to modulate drug release by using nanoparticulates (NPs) as carriers. In this study, methotrexate-loaded chitosan–polyanion nanoparticles were produced by polyelectrolyte complexation assisted by...

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Detalles Bibliográficos
Autores principales: Ciro, Yhors, Rojas, John, Alhajj, Maria J., Carabali, Gustavo A., Salamanca, Constain H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168905/
https://www.ncbi.nlm.nih.gov/pubmed/31936208
http://dx.doi.org/10.3390/ph13010011