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Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review
It is over 50 years since the discovery of microtubules, and they have become one of the most important drug targets for anti-cancer therapies. Microtubules are predominantly composed of the protein tubulin, which contains a number of different binding sites for small-molecule drugs. There is contin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168938/ https://www.ncbi.nlm.nih.gov/pubmed/31947889 http://dx.doi.org/10.3390/ph13010008 |