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High-mobility group box 1 protein antagonizes the immunosuppressive capacity and therapeutic effect of mesenchymal stem cells in acute kidney injury

BACKGROUND: Kidney ischemia reperfusion injury (IRI) is a common cause of acute kidney injury and an unavoidable consequence of kidney transplantation and still lacks specific therapeutics. Recently, mesenchymal stem cell (MSC) has been emerging as a promising cell-based therapy for IRI in the conte...

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Detalles Bibliográficos
Autores principales: Wang, Shuo, Cai, Songjie, Zhang, Weitao, Liu, Xigao, Li, Yan, Zhang, Chao, Zeng, Yigang, Xu, Ming, Rong, Ruiming, Yang, Tianshu, Shi, Benkang, Chandraker, Anil, Yang, Cheng, Zhu, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169035/
https://www.ncbi.nlm.nih.gov/pubmed/32312307
http://dx.doi.org/10.1186/s12967-020-02334-8