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Metabolic Stability of New Mito-Protective Short-Chain Naphthoquinones

Short-chain quinones (SCQs) have been identified as potential drug candidates against mitochondrial dysfunction, which is largely dependent on their reversible redox characteristics of the active quinone core. We recently synthesized a SCQ library of > 148 naphthoquinone derivatives and identifie...

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Detalles Bibliográficos
Autores principales: Feng, Zikai, Smith, Jason A., Gueven, Nuri, Quirino, Joselito P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169385/
https://www.ncbi.nlm.nih.gov/pubmed/32059451
http://dx.doi.org/10.3390/ph13020029