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TTF-1/p63-Positive Poorly Differentiated NSCLC: A Histogenetic Hypothesis from the Basal Reserve Cell of the Terminal Respiratory Unit

TTF-1 is expressed in the alveolar epithelium and in the basal cells of distal terminal bronchioles. It is considered the most sensitive and specific marker to define the adenocarcinoma arising from the terminal respiratory unit (TRU). TTF-1, CK7, CK5/6, p63 and p40 are useful for typifying the majo...

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Detalles Bibliográficos
Autores principales: Cabibi, Daniela, Bellavia, Sandro, Giannone, Antonino Giulio, Barraco, Nadia, Cipolla, Calogero, Martorana, Anna, Rodolico, Vito, Cajozzo, Massimo, Florena, Ada Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169837/
https://www.ncbi.nlm.nih.gov/pubmed/31935792
http://dx.doi.org/10.3390/diagnostics10010025