SPHK2-Generated S1P in CD11b(+) Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

Acute lung injury (ALI) is a lethal inflammatory lung disorder whose incidence is on the rise. Alveolar macrophages normally act to resolve inflammation, but when dysregulated they can provoke ALI. We demonstrate that monocyte-derived macrophages (CD11b(+) macrophages) recruited into the airspace up...

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Detalles Bibliográficos
Autores principales: Joshi, Jagdish C., Joshi, Bhagwati, Rochford, Ian, Rayees, Sheikh, Akhter, Md Zahid, Baweja, Sukriti, Chava, Koteshwara Rao, Tauseef, Mohammad, Abdelkarim, Hazem, Natarajan, Viswanathan, Gaponenko, Vadim, Mehta, Dolly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170050/
https://www.ncbi.nlm.nih.gov/pubmed/32209471
http://dx.doi.org/10.1016/j.celrep.2020.02.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170050/
https://www.ncbi.nlm.nih.gov/pubmed/32209471
http://dx.doi.org/10.1016/j.celrep.2020.02.112

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