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Inhaled biguanides and mTOR inhibition for influenza and coronavirus (Review)

The mammalian target of rapamycin (mTOR) signaling pathway senses and responds to nutrient availability, energy sufficiency, stress, hormones and mitogens to modulate protein synthesis. Rapamycin is a bacterial product that can inhibit mTOR via the PI3K/AKT/mTOR pathway. mTOR signaling is necessary...

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Detalles Bibliográficos
Autor principal: LEHRER, STEVEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170270/
https://www.ncbi.nlm.nih.gov/pubmed/32313883
http://dx.doi.org/10.3892/wasj.2020.42