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Inhaled biguanides and mTOR inhibition for influenza and coronavirus (Review)
The mammalian target of rapamycin (mTOR) signaling pathway senses and responds to nutrient availability, energy sufficiency, stress, hormones and mitogens to modulate protein synthesis. Rapamycin is a bacterial product that can inhibit mTOR via the PI3K/AKT/mTOR pathway. mTOR signaling is necessary...
Autor principal: | LEHRER, STEVEN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170270/ https://www.ncbi.nlm.nih.gov/pubmed/32313883 http://dx.doi.org/10.3892/wasj.2020.42 |
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