YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators

The N(6)-methyladenosine (m(6)A) modification regulates mRNA stability and translation. Here, we show that transcriptomic m(6)A modification can be dynamic and the m(6)A reader protein YTH N(6)-methyladenosine RNA binding protein 2 (YTHDF2) promotes mRNA decay during cell cycle. Depletion of YTHDF2...

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Detalles Bibliográficos
Autores principales: Fei, Qili, Zou, Zhongyu, Roundtree, Ian A., Sun, Hui-Lung, He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170294/
https://www.ncbi.nlm.nih.gov/pubmed/32267835
http://dx.doi.org/10.1371/journal.pbio.3000664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170294/
https://www.ncbi.nlm.nih.gov/pubmed/32267835
http://dx.doi.org/10.1371/journal.pbio.3000664

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