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Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors

Oxidative stress is one of the main causes of significant severe diseases. The discovery of new potent antioxidants with high efficiency and low toxicity is a great demand in the field of medicinal chemistry. Herein, we report the design, synthesis molecular modelling and biological evaluation of no...

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Detalles Bibliográficos
Autores principales: Ali, Sahar A., Awad, Samir Mohamed, Said, Ahmed Mohammed, Mahgoub, Shahenda, Taha, Heba, Ahmed, Naglaa Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170299/
https://www.ncbi.nlm.nih.gov/pubmed/32216479
http://dx.doi.org/10.1080/14756366.2020.1742116