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Imidazopyridine-fused [1,3]diazepinones: modulations of positions 2 to 4 and their impacts on the anti-melanoma activity

A series of 19 novel pyrido-imidazodiazepinones, with modulations of positions 2, 3 and 4 of the diazepine ring were synthesised and screened for their in vitro cytotoxic activities against two melanoma cell lines (A375 and MDA-MB-435) and for their potential toxicity against NIH-3T3 non-cancerous c...

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Detalles Bibliográficos
Autores principales: Baccon-Sollier, Paul Le, Malki, Yohan, Maye, Morgane, Ali, Lamiaa M. A., Lichon, Laure, Cuq, Pierre, Vincent, Laure-Anaïs, Masurier, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170309/
https://www.ncbi.nlm.nih.gov/pubmed/32249633
http://dx.doi.org/10.1080/14756366.2020.1748024