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Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae

We report a case of a 63-year-old female patient who developed a recurrent urinary tract infection (UTI) with extensively drug-resistant Klebsiella pneumoniae (ERKp). In the initial two rounds of phage therapy, phage resistant mutants developed within days. Although ERKp strains were completely resi...

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Detalles Bibliográficos
Autores principales: Bao, Juan, Wu, Nannan, Zeng, Yigang, Chen, Liguang, Li, Linlin, Yang, Lan, Zhang, Yiyuan, Guo, Mingquan, Li, Lisha, Li, Jie, Tan, Demeng, Cheng, Mengjun, Gu, Jingmin, Qin, Jinghong, Liu, Jiazheng, Li, Shiru, Pan, Guangqiang, Jin, Xin, Yao, Bangxin, Guo, Xiaokui, Zhu, Tongyu, Le, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170350/
https://www.ncbi.nlm.nih.gov/pubmed/32212918
http://dx.doi.org/10.1080/22221751.2020.1747950