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Neuronal mitochondria-targeted therapy for Alzheimer’s disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems

Reactive oxygen species (ROS)-induced neuronal mitochondrial dysfunction is a key pathologic factor in sporadic Alzheimer’s disease (AD). Neuronal mitochondria have been proposed to be a promising therapeutic target for AD, especially for the failures of phase III clinical trials on conventional amy...

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Detalles Bibliográficos
Autores principales: Han, Yang, Chu, Xiaoyang, Cui, Lin, Fu, Shiyao, Gao, Chunsheng, Li, Yi, Sun, Baoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170363/
https://www.ncbi.nlm.nih.gov/pubmed/32228100
http://dx.doi.org/10.1080/10717544.2020.1745328