Lasmiditan inhibits calcitonin gene-related peptide release in the rodent trigeminovascular system

Migraine headache pathophysiology involves trigeminovascular system activation, calcitonin gene-related peptide (CGRP) release, and dysfunctional nociceptive transmission. Triptans are 5-HT(1B/1D/(1F)) receptor agonists that prejunctionally inhibit trigeminal CGRP release, but their vasoconstrictor...

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Detalles Bibliográficos
Autores principales: Labastida-Ramírez, Alejandro, Rubio-Beltrán, Eloísa, Haanes, Kristian A., Chan, Kayi Y., Garrelds, Ingrid M., Johnson, Kirk W., Danser, Alexander H.J., Villalón, Carlos M., MaassenVanDenBrink, Antoinette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170441/
https://www.ncbi.nlm.nih.gov/pubmed/31977930
http://dx.doi.org/10.1097/j.pain.0000000000001801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170441/
https://www.ncbi.nlm.nih.gov/pubmed/31977930
http://dx.doi.org/10.1097/j.pain.0000000000001801

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