An unbiased and efficient assessment of excitability of sensory neurons for analgesic drug discovery

Alleviating chronic pain is challenging, due to lack of drugs that effectively inhibit nociceptors without off-target effects on motor or central neurons. Dorsal root ganglia (DRG) contain nociceptive and non-nociceptive neurons. Drug screening on cultured DRG neurons, rather than cell lines, allows...

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Detalles Bibliográficos
Autores principales: Mohammed, Zainab A., Kaloyanova, Katerina, Nassar, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170445/
https://www.ncbi.nlm.nih.gov/pubmed/31929383
http://dx.doi.org/10.1097/j.pain.0000000000001802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170445/
https://www.ncbi.nlm.nih.gov/pubmed/31929383
http://dx.doi.org/10.1097/j.pain.0000000000001802

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