Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer

The mechanistic target of rapamycin (mTOR) is a PI3K-related kinase that regulates cell growth, proliferation and survival in response to the availability of energy sources and growth factors. Cancer development and progression is often associated with constitutive activation of the mTOR pathway, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Antoch, Marina P., Wrobel, Michelle, Gillard, Bryan, Kuropatwinski, Karen K., Toshkov, Ilia, Gleiberman, Anatoli S., Karasik, Ellen, Moser, Michael T., Foster, Barbara A., Andrianova, Ekaterina L., Chernova, Olga V., Gudkov, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170500/
https://www.ncbi.nlm.nih.gov/pubmed/32341756
http://dx.doi.org/10.18632/oncotarget.27550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170500/
https://www.ncbi.nlm.nih.gov/pubmed/32341756
http://dx.doi.org/10.18632/oncotarget.27550

Ejemplares similares