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Development of a novel β-1,6-glucan–specific detection system using functionally-modified recombinant endo-β-1,6-glucanase

β-1,3-d-Glucan is a ubiquitous glucose polymer produced by plants, bacteria, and most fungi. It has been used as a diagnostic tool in patients with invasive mycoses via a highly-sensitive reagent consisting of the blood coagulation system of horseshoe crab. However, no method is currently available...

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Detalles Bibliográficos
Autores principales: Yamanaka, Daisuke, Takatsu, Kazushiro, Kimura, Masahiro, Swamydas, Muthulekha, Ohnishi, Hiroaki, Umeyama, Takashi, Oyama, Fumitaka, Lionakis, Michail S., Ohno, Naohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170528/
https://www.ncbi.nlm.nih.gov/pubmed/32132174
http://dx.doi.org/10.1074/jbc.RA119.011851