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Salvianolic Acid Alleviated Blood–Brain Barrier Permeability in Spontaneously Hypertensive Rats by Inhibiting Apoptosis in Pericytes via P53 and the Ras/Raf/MEK/ERK Pathway

OBJECTIVE: To investigate the effect of salvianolic acid A (SA) on the permeability of blood–brain barrier (BBB) and brain microvascular pericyte apoptosis in spontaneously hypertensive rats (SHR). METHODS: Evans Blue was used to determine the BBB permeability in control rats and SHR. Western blotti...

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Detalles Bibliográficos
Autores principales:	Wu, Qingbin, Yuan, Xiaochen, Li, Bingwei, Han, Ruiqin, Zhang, Honggang, Xiu, Ruijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170553/ https://www.ncbi.nlm.nih.gov/pubmed/32368011 http://dx.doi.org/10.2147/DDDT.S245959

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